Behavioral nudges can help improve vaccine uptake, but there have been limited studies on this in low- and middle-income countries, especially in Africa. To support the ongoing efforts of the National Department of Health and partners in accelerating the uptake of COVID-19 vaccines, Project Last Mile collaborated with Ipsos to undertake the first nationally representative study in South Africa. The study aimed to understand and explore the feasibility of incentive programs and behavioral nudges to improve COVID-19 vaccination rates.